S
SAMHSA - Substance Abuse and Mental Health Services Administration (agency providing educational services and assistance to those involved in drug abuse programs and mental health services)
SBA - Small Business Administration (federal agency created in 1953 to provide financial and management assistance to small businesses)
SC - Space Command (newly created military service organization intended to provide recruits and capabilities in the exploration and defense of space)
SC - Strategic Command (Department of Defense (DoD) agency which serves to coordinate military operations)
SCOTUS - Supreme Court of the U.S. (highest court of the U.S. judicial system, which issues final decisions in federal cases and oversees the lower federal courts)
SEC - Securities and Exchange Commission (federal agency created under the Securities Exchange Act of 1934 to enforce the Securities Act of 1933, with overall responsibility for regulating the U.S. securities markets)
SFOC - Special Forces Operations Command (division of the Department of Defense (DoD) which oversees the operations of Special Forces)
SIP - Seafood Inspection Program (agency within the Department of Agriculture which monitors and regulates food safety in the area of seafood)
SLSDC - Saint Lawrence Seaway Development Corporation (agency which oversees planning and development for construction projects along the Saint Lawrence River primarily focused on commercial and trade development)
SPA - Southeastern Power Administration (federal agency which oversees electric/energy generation for the Southeastern region of the U.S.)
SPA - Southwestern Power Administration (federal agency which oversees electric/energy generation for the Southwestern region of the U.S.)
SRBC - Susquehanna River Basin Commission (agency which deals with commercial planning and development along the Susquehanna River)
SSA - Social Security Administration (federal agency which administers the social insurance program (Social Security) providing benefits to retirees and other benefiaries of the program)
SSAB - Social Security Advisory Board (federal agency which provides advice and oversees the Social Security Administration (SSA))
SSS - Selective Service System (agency which administers the military draft system used to provide a manpower pool for the military in case of need)
STB - Surface Transportation Board