O
OCC - Office of the Comptroller of the Currency (bureau of the Treasury Department, originally established in 1863, which charters, regulates, and supervises national banks and federal savings associations)
OCC - Options Clearing Corporation (corporation, owned by the stock exchanges, providing trade comparison and settlement services for all option trades on U.S. securities exchanges)
OCPD - Office of Community Planning and Development
OCR - Office for Civil Rights (Education Department) (division within the Department of Education responsible for enforcement of anti-discrimination laws involving federal grants to colleges and universities)
OCR - Office for Civil Rights (Health and Human Services) (division within the Department of Health and Human Services (HHS) which has enforced the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule since 2003 and took over enforcement of the Security Rule from the Centers for Medicare and Medicaid Services (CMS) in July 2009, as a result of the Health Information Technology for Economic and Clinical Health (HITECH) Act)
OCSE - Office of Child Support Enforcement
ODEP - Office of Disability Employment Policy
ODNI - Office of the Director of National Intelligence (office created by the Intelligence Reform and Terrorism Prevention Act (IRTPA) of 2004 designed to coordinate intelligence gathering and consolidate intelligence activities within one agency)
OFAC - Office of Foreign Assets Control (agency within the Treasury Department which administers and enforces economic and trade sanctions based on U.S. foreign policy and national security goals against targeted individuals)
OFR - Office of the Federal Register (agency which compiles and publishes the official record of U.S. laws codified in the Federal Register)
OGE - Office of Government Ethics (agency which oversees ethical conduct by government/elected officials)
OMB - Office of Management and Budget (agency within the Office of the President responsible for preparing the president's budget, development of fiscal programs, reviewing agency performance, and advising the president on legislative matters)
ONDCP - Office of National Drug Control Policy (agency dealing with issues related to the control of illegal drugs)
OPA - Office of the Pardon Attorney (agency which reviews requests for pardons and makes recommendations to the president)
OPM - Office of Personnel Management (agency which administers the personnel system for federal employees)
ORNL - Oak Ridge National Laboratory (Department of Energy research facility which conducts research primarily involving nuclear reactors and also other scientific areas)
OSC - Office of Special Counsel (independent federal agency which investigates limited areas when requested by Congress)
OSERS - Office of Special Education and Rehabilitative Services (agency which focuses on the needs of special education teachers and students and rehabilitative services)
OSHA - Occupational Safety and Health Administration (agency which studies safety and health issues related to workplace conditions for employees)
OSHRC - Occupational Safety and Health Review Commission ()
OSMRE - Office of Surface Mining, Reclamation and Enforcement ()
OSS - Office of Strategic Services (intelligence agency created in 1942 to collect and analyze information, and conduct operations in furtherance of the war effort - predecessor of the Central Intelligence Agency (CIA), created in 1947)
OSTP - Office of Science and Technology Policy (agency established in 1976 to advise the president and the Executive Branch on current science and technology issues)
OTS - Office of Thrift Supervision (federal agency established in 1989 to supervise thrift institutions with federal charters - OTS was abolished in 2011 by the Dodd-Frank Act)
OVW - Office on Violence Against Women (agency which studies societal violence against women and provides support for programs designed to provide solutions)